Colorado Blood Cancer Institute Medical Group

Colorado Blood Cancer Institute Medical GroupColorado Blood Cancer Institute Medical GroupColorado Blood Cancer Institute Medical Group

Colorado Blood Cancer Institute Medical Group

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Amyloidosis Staging

Cardiac

Marker/Thresholds:  

  • NT-proBNP > 332 ng/L
  • cTnT > 0.035 ng/mL

Stages:

  • I. no markers above cutoffs
  • II. one marker above cutoffs
  • IIIa. both markers above cutoffs and NT-proBNP < 8500 ng/L
  • IIIb. both markers above cutoffs and NT-proBNP 8500 ng/L or higher


Revised Mayo

Marker/Thresholds:

  • NT-proBNP > 1800 ng/L
  • cTnT >0.025 ng/mL
  • dFLC > 180 mg/L

Stages: 

  • I. 0 markers above cutoffs
  • II. 1 marker above cutoffs
  • III. 2 markers above cutoffs
  • IV. 3 markers above cutoffs


Renal

Marker/Thresholds:

  • eGFR < 50 mL/min/1.73m^2
  • Proteinuria > 5g/24h

Stages:

  • I. both eGFR above and proteinuria below cutoffs
  • II. either eGFR below or proteinuria above cutoffs
  • III. both eGFR below and proteinuria above cutoffs

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